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01.04.2024 | Research

At-home bleaching with carbamide peroxide with concentrations below 10%: bleaching efficacy and permeability in the pulp chamber

verfasst von: Deisy Cristina Ferreira Cordeiro, Michael Willian Favoreto, Gabrielle Gomes Centenaro, Fernanda Novak Gumy, Alessandro D. Loguercio, Christiane Philippini Ferreira Borges, Alessandra Reis

Erschienen in: Clinical Oral Investigations | Ausgabe 4/2024

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Abstract

Objectives

To evaluate the bleaching efficacy and permeability of hydrogen peroxide (HP) in the pulp chamber of human teeth bleached with lower concentrations of carbamide peroxide gel (4%, 5% and 7% CP).

Materials and methods

Bleaching gels with lower concentrations were formulated and a commercial standard gel, 10% CP, was used as a reference. Fifty-six human premolars were randomly divided into four groups. Applications of the bleaching gel were made for 3 h for 21 days. The bleaching efficacy was evaluated by digital spectrophotometry on 1, 7, 14 and 21 days, with analysis in the ∆E_ab, ∆E₀₀ and WI_D color spaces. The concentration of HP in the pulp chamber was measured in the same periods by UV-Vis spectrophotometry (µg/mL). Two-way repeated analysis of variance (ANOVA) examined bleaching efficacy and HP permeability, followed by Tukey’s post-hoc test (α = 0.05).

Results

All groups showed significant color changes, with no statistical differences after the second and third week of bleaching (p > 0.05). The ‘time’ factor was statistically different (p < 0.05), increasing the bleaching efficacy throughout the treatment. The 4% CP group had lower HP levels in the pulp chamber (p < 0.05).

Conclusions

The results seem promising, revealing that low concentration gels are as effective as 10% CP with the benefit of reducing the amount of HP in the pulp chamber.

Clinical relevance

Low concentration 4% PC and 5% PC maintains bleaching efficacy, reduces the penetration of HP peroxide into the pulp chamber, and may reduce tooth sensitivity.

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Titel: At-home bleaching with carbamide peroxide with concentrations below 10%: bleaching efficacy and permeability in the pulp chamber
verfasst von: Deisy Cristina Ferreira Cordeiro
Michael Willian Favoreto
Gabrielle Gomes Centenaro
Fernanda Novak Gumy
Alessandro D. Loguercio
Christiane Philippini Ferreira Borges
Alessandra Reis
Publikationsdatum: 01.04.2024
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 4/2024
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-024-05604-7

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At-home bleaching with carbamide peroxide with concentrations below 10%: bleaching efficacy and permeability in the pulp chamber