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Intensive Care Medicine OnlineFirst articles

29.05.2024 | Editorial

Broad use of processed EEG: ready for prime time yet?

Processed EEG is commonly used in the operating room and has recently been introduced to the intensive care unit (ICU) setting [ 1 , 3 ]. DoA-S indices, dimensionless scaled index values ranging from 0 (total EEG suppression) to 100 (full …

verfasst von:
Frank A. Rasulo, Jan Claassen, Stefano Romagnoli

28.05.2024 | Correspondence

Methodological considerations in meta-analysis: evaluating RCTs, NRS, and crossover trials for electrical impedance tomography in PEEP titration

verfasst von:
Nickjaree Songsangvorn, Arthur S. Slutsky, Karen E. A. Burns, Haibo Zhang

28.05.2024 | Editorial

Managing perioperative myocardial injury

Myocardial injury during the peri-operative period is a heterogeneous syndrome reflecting different pathophysiologies (ischemic and non-ischemic, cardiac and extra-cardiac) and carrying different prognoses. Relevant peri-operative cardiac …

verfasst von:
Michelle S. Chew, Christian Puelacher, Giovanna Lurati-Buse

28.05.2024 | Correspondence

Long-term outcomes of critically ill patients with hematological malignancies: what is the impact of the coronavirus disease 2019 pandemic?

verfasst von:
Lavi Oud

27.05.2024 | Editorial

How to use facemask noninvasive ventilation

In the acute setting, facemask NIV is usually administered through an oronasal or a full-face interface, with similar efficacy. Facemasks are designed to create an airtight seal and are equipped with adjustable straps and cushioning to enhance …

verfasst von:
Bruno L. Ferreyro, Audrey De Jong, Domenico Luca Grieco

27.05.2024 | Editorial

Implementing diaphragm protection during invasive mechanical ventilation

Diaphragmatic activity cannot be accurately inferred from ventilator settings [ 2 ]. Diaphragm protection therefore requires direct monitoring of diaphragmatic effort. The reference technique is measurement of transdiaphragmatic pressure using a …

verfasst von:
Ewan C. Goligher, L. Felipe Damiani, Bhakti Patel

Open Access 27.05.2024 | Narrative Review

Heterogeneity in the definition of major adverse kidney events: a scoping review

Acute kidney injury (AKI) is associated with persistent renal dysfunction, the receipt of dialysis, dialysis dependence, and mortality. Accordingly, the concept of major adverse kidney events (MAKE) has been adopted as an endpoint for assessing …

verfasst von:
Akinori Maeda, Ryota Inokuchi, Rinaldo Bellomo, Kent Doi

27.05.2024 | Editorial

Outcome of hospital-acquired bloodstream infection: interplay between bacteria, host, and healthcare system organization

verfasst von:
Nicolas Mongardon, Jean-Louis Vincent

23.05.2024 | Correspondence

Lactate levels in sepsis: don’t forget the mitochondria

verfasst von:
Wagner Luis Nedel, Luis Valmor Portela

Open Access 22.05.2024 | Correspondence

Norepinephrine dose reporting: are we looking at different sides of the same coin?

verfasst von:
Miguel Ibarra-Estrada, Eduardo Kattan, Christian Jung

21.05.2024 | Guidelines

European Society of Intensive Care Medicine clinical practice guideline on fluid therapy in adult critically ill patients. Part 1: the choice of resuscitation fluids

Administration of resuscitation fluids is common in the management of critically ill patients [ 1 ]. The European Society of Intensive Care Medicine (ESICM) convened a group of content and method experts to issue a clinical practice guideline (CPG) …

verfasst von:
Yaseen M. Arabi, Emilie Belley-Cote, Andrea Carsetti, Daniel De Backer, Katia Donadello, Nicole P. Juffermans, Naomi Hammond, Jon Henrik Laake, Dawei Liu, Kathryn Maitland, Antonio Messina, Morten Hylander Møller, Daniele Poole, Rob Mac Sweeney, Jean-Louis Vincent, Fernando G. Zampieri, Fayez AlShamsi, European Society of Intensive Care Medicine

21.05.2024 | Correspondence

The role of pleural pressure and airway closure during mechanical ventilation

verfasst von:
Jan van Egmond, Jan Mulier

Open Access 21.05.2024 | Narrative Review

Nutrition in the intensive care unit: from the acute phase to beyond

Recent randomized controlled trials (RCTs) have shown no benefit but dose-dependent harm by early full nutritional support in critically ill patients. Lack of benefit may be explained by anabolic resistance, suppression of cellular repair …

verfasst von:
Angelique M. E. de Man, Jan Gunst, Annika Reintam Blaser

21.05.2024 | Editorial

Setting the ventilator in acute brain injury

When selecting IMV settings, a reasonable first step is to set Vt between 4 and 8 ml kg −1 of predicted body weight (PBW) [ 3 ], while ensuring that plateau pressure (Pplat) is ≤ 30 cmH 2 O. Vt in this range is deemed safe in most patients with …

verfasst von:
Raphaël Cinotti, Shaurya Taran, Robert D. Stevens

21.05.2024 | Editorial

Winning hearts and minds: the impact of illness severity and pre-morbid mental health on wellbeing after acute myocardial infarction with cardiogenic shock

verfasst von:
Walter Schiffer, Nancy K. Sweitzer, Christian Jung

Open Access 21.05.2024 | Correspondence

Routine colonoscopy in patients with high risk of non-occlusive mesenteric ischemia

verfasst von:
Alexander Supady, Hannes Neeff, Tobias Wengenmayer, Dominik Bettinger

21.05.2024 | Correspondence

The choice of crystalloid type in the intensive care unit is likely more complex than expected: should doubt benefit the patient?

verfasst von:
Gildas Gueret, Sabine Lemoine, Pascale Le Maguet

16.05.2024 | Editorial

Treating necrotizing skin and soft-tissue infections

Typical cases are usually readily identified on clinical grounds, leading to early emergency admission and source control. In contrast, underestimation of the burden of comorbidities, slow onset or atypical symptoms without sepsis, are common risk …

verfasst von:
Philippe Montravers, Anna Norrby-Teglund, Patricia Munoz

16.05.2024 | Letter

Volatile sedation practices in patients with severe acute respiratory distress syndrome under VV-ECMO support

verfasst von:
Sara Alcántara Carmona, Ana del Saz, Sofía Contreras, Jordi Riera, Aaron Blandino, the Volatile Sedation on VV-ECMO Research Group

15.05.2024 | Systematic Review

Interventions for improving critical care in low- and middle-income countries: a systematic review

Quality improvement (QI) interventions aim to systematically change a predefined process or pathway of patient care, and often target timeliness, efficiency, effectiveness, equity, and safety of care delivery [ 1 ]. Intervention strategies …

verfasst von:
Duncan Wagstaff, Sumaiya Arfin, Alba Korver, Patrick Chappel, Aasiyah Rashan, Rashan Haniffa, Abi Beane