Introduction
Methods
Results
Group A | Group B | p value | |
---|---|---|---|
(< 74 years) (N = 118) | (≥ 75 years) (N = 102) | ||
Age, years | 65 [55, 69] | 80 [77, 84] | < 0.0001* |
Gender (female), N (%) | 42 (36) | 41 (40) | 0.48 |
Height, cm | 162 ± 9 | 156 ± 9 | < 0.0001* |
Weight, kg | 56 [48, 64] | 51 [46, 57] | 0.0008* |
Body mass index, kg/m2 | 21.4 [18.8, 24.5] | 21.3 [18.8, 23.5] | 0.61 |
Reason of ICU admission | |||
Non-surgical, N (%) | 31 (26) | 42 (41) | 0.02* |
Surgical, N (%) | 87 (74) | 60 (59) | |
Physical status before ICU admission | 0.47 | ||
Good physical status, N (%) | 96 (82) | 79 (77) | |
Poor physical status, N (%) | 22 (18) | 22 (23) | |
Residence before hospitalization (home), N (%) | 115 (97) | 96 (94) | 0.21 |
Comorbidity at hospitalization | |||
Hypertension, N (%) | 56 (47) | 62 (61) | 0.048* |
Diabetes mellitus, N (%) | 37 (31) | 23 (23) | 0.14 |
Heart disease, N (%) | 30 (25) | 52 (51) | < 0.0001* |
Cerebral stroke, N (%) | 20 (17) | 31 (30) | 0.02* |
Cancer, N (%) | 53 (45) | 24 (24) | 0.009* |
Acute kidney injury, N (%) | 24 (20) | 29 (28) | 0.16 |
APACHE II | 18 [13, 25] | 23 [17, 33] | < 0.0001* |
SOFA | 6 ± 3 | 6 ± 3 | 0.20 |
Use of catecholamine on ICU admission day, N (%) | 83 (70) | 68 (67) | 0.56 |
Use of renal replacement therapy, N (%) | 24 (20) | 22 (22) | 0.82 |
Duration of ventilation days | 3 [2, 5] | 4 [2, 8] | 0.03* |
Length of ICU stay days | 5 [4, 9] | 7 [4, 10] | 0.09 |
Length of hospital stay days | 36 [23, 55] | 39 [24, 58] | 0.24 |
Hospital mortality, N (%) | 23 (19) | 26 (25) | 0.29 |
Non-surgical, N (%) | 16 (52) | 18 (43) | 0.46 |
Surgical, N (%) | 7 (8) | 8 (13) | 0.30 |
Good physical status at hospital discharge, N (%) | 86 (91) | 56 (74) | 0.004* |
Discharge to home, N (%) | 68 (72) | 28 (37) | < 0.0001* |
A) Group A (< 74 years) | |||
Surgery (N = 87) | Non-surgery (N = 31) | p value | |
Hospital mortality, N (%) | 7 (8) | 16 (52) | < 0.0001* |
N = 80 | N = 15 | ||
Good physical status at hospital discharge, N (%) | 76 (95) | 10 (67) | < 0.0001* |
Discharge to home, N (%) | 61 (76) | 7 (47) | < 0.0001* |
B) Group B (≥ 75 years) | |||
Surgery (N = 60) | Non-surgery (N = 42) | p value | |
Hospital mortality, N (%) | 8 (13) | 18 (43) | < 0.0001* |
N = 52 | N = 24 | ||
Good physical status at hospital discharge, N (%) | 42 (81) | 14 (58) | 0.04* |
Discharge to home, N (%) | 24 (46) | 4 (17) | 0.01* |
A) Hospital mortality | |||
Reference | Odds ratio [95%CI] | p value | |
Age | < 74 years | 1.02 [0.44–2.38] | 0.96 |
Reason of ICU admission | Surgery | 1.64 [0.60–4.39] | 0.33 |
APACHE II | – | 1.14 [1.08–1.21] | < 0.0001* |
Hypertension | No | 0.54 [0.24–1.21] | 0.13 |
Heart disease | No | 0.76 [0.32–1.76] | 0.52 |
Cerebral stroke | No | 0.73 [0.28–1.78] | 0.50 |
Cancer | No | 0.79 [0.31–2.03] | 0.63 |
B) Physical status at hospital discharge | |||
Reference | Odds ratio [95%CI] | p value | |
Age | – | 1.05 [1.01–1.11] | 0.02* |
Reason of ICU admission | Surgery | 1.77 [0.56–5.40] | 0.33 |
Residence before hospitalization | Home | 3.94 [0.32–95.1] | 0.29 |
APACHE II | – | 1.05 [0.98–1.13] | 0.15 |
Duration of ventilation | – | 1.13 [1.03–1.25] | 0.009* |
C) Discharge destination | |||
Reference | Odds ratio [95%CI] | p value | |
Age | – | 1.06 [1.03–1.10] | 0.0002* |
Reason of ICU admission | Surgery | 2.57 [0.95–7.34] | 0.06 |
Residence before hospitalization | Home | – | 0.17 |
APACHE II | – | 1.00 [0.94–1.09] | 0.77 |
SOFA | – | 1.04 [0.88–1.23] | 0.65 |
Duration of ventilation | – | 1.10 [1.01–1.24] | 0.03* |
A) Physical function at hospital discharge | |||
Good (N = 142) | Poor (N = 29) | p value | |
Age, years | 69.5 [64, 80] | 82 [69.5, 87] | 0.001* |
Gender (female), N (%) | 51 (36) | 14 (48) | 0.21 |
Body Mass Index, kg/m2 | 21.3 [18.9, 24.2] | 20.2 [17.4, 23.8] | 0.22 |
Reason of ICU admission | |||
Surgical, N (%) | 118 (83) | 14 (48) | 0.0001* |
Physical status before ICU admission | |||
Good physical status, N (%) | 128 (90) | 24 (83) | 0.25 |
Residence before hospitalization (home), N (%) | 141 (99) | 26 (90) | 0.001* |
APACHE II | 18 [14, 23] | 25 [19, 34] | < 0.0001* |
SOFA | 5 ± 3 | 6 ± 3 | 0.06 |
Use of renal replacement therapy, N (%) | 23 (16) | 3 (10) | 0.42 |
Duration of ventilation days | 3 [2, 4] | 6 [3. 10.5] | < 0.0001* |
B) Discharge destination | |||
Home (N = 96) | Other (N = 75) | p value | |
Age, years | 68 [59, 75.8] | 79 [69, 83] | < 0.0001* |
Gender (female), N (%) | 34 (35) | 31 (41) | 0.21 |
Body mass index, kg/m2 | 21.7 [19.3, 24.1] | 20.6 [17.7, 24.1] | 0.08 |
Reason of ICU admission | |||
Surgical, N (%) | 85 (89) | 47 (63) | < 0.0001* |
Physical status before ICU admission | |||
Good physical status, N (%) | 88 (92) | 64 (85) | 0.19 |
Residence before hospitalization (home), N (%) | 96 (100) | 71 (95) | 0.02* |
APACHE II | 17 [14, 23] | 22 [17, 27] | < 0.0001* |
SOFA | 5 ± 2 | 6 ± 3 | 0.01* |
Use of renal replacement therapy, N (%) | 11 (11) | 15 (20) | 0.12 |
Duration of ventilation days | 3 [2, 4] | 4 [2. 8] | 0.0002* |